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If you install the Setup files to this path, including OCSCore.msi, the rest of the Skype for Business Server files will be deployed to this drive too.
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If your organization requires that you locate Internet Information Services (IIS) and all Web Services on a drive other than the system drive, you can change the installation location path for the Skype for Business Server files in the Setup dialog box. Change this path to another location or drive if you need to have the files installed to another location. On the Installation Location page, click OK. If you are prompted to install the Microsoft Visual C++ distributable, click Yes. Locate the installation media on your computer, and then double-click \Setup\amd64\Setup.exe. If you are logged on as a standard user in Windows and User Account Control (UAC) is enabled, you will be prompted for the local administrator or a domain equivalent user name and password.
Log on as a local administrator (minimum requirement) to the computer where you want to install the administrative tools. If you install the Setup files to this path, including OCSCore.msi, the rest of the Skype for Business Server files will be deployed to this drive as well.
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